GRIK2 antibody (AA 652-701)

Catalog No. ABIN6736391

The Rabbit Polyclonal anti-GRIK2 antibody (ABIN6736391) specifically detects GRIK2 in WB, IHC and IHC (p). The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Bat, Chicken, Monkey, Pig and Xenopus laevis samples.

Quick Overview for GRIK2 antibody (AA 652-701) (ABIN6736391)

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Bat, Chicken, Monkey, Pig, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GRIK2 Antibody

Binding Specificity: AA 652-701

Specificity: Human GRIK2

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig, Chicken, Xenopus (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa652-701 of human GRIK2 (Q96KS6, NP_786944). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard, Xenopus (100%), Stickleback (85%), Trout, Zebrafish (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.12 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Alternative Name: GRIK2 / GLUR6

Background: Name/Gene ID: GRIK2
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIK2, BA487F5.1, GluR-6, Glur5-7, GLUR6, Glutamate receptor form A, Glutamate receptor form B, EAA4, Glutamate receptor form C, GLR6, GLUK6, Glutamate receptor form E, MRT6, GluK2, Glutamate receptor 6, Glutamate receptor form D

Gene ID: 2898

NCBI Accession: NP_786944

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity