CD11b antibody (Extracellular Domain)

Catalog No. ABIN1493518

This Chicken Polyclonal antibody specifically detects CD11b in IHC. It exhibits reactivity toward Human.

Quick Overview for CD11b antibody (Extracellular Domain) (ABIN1493518)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CD11b Antibody

Binding Specificity: Extracellular Domain

Purification: Ig fraction

Immunogen: Keyhole Limpet Hemocyanin (KLH)-conjugate of a synthetic peptide corresponding to a region near the center of the extracellular domain of this single-membrane pass gene product

Type of Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Phosphate-buffered (10 mM) isotonic saline (0.9 % , w.v) saline (PBS,  pH 7.2) with 50 % (v/v) glycerol and sodium azide (0.02 %, w/v). The glycerol allows storage at -20C without freezing, Sodium azide is added as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Sensitive to light.

Storage: 4 °C

Storage Comment: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 1 year. Protect from light.

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: ITGAM / CD11b

Background: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gene ID: 3684

UniProt: P11215

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation