Caspase 8 antibody (AA 1-376)

Catalog No. ABIN6757702

This Mouse Monoclonal antibody specifically detects Caspase 8 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (AA 1-376) (ABIN6757702)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Caspase 8 Antibody

Binding Specificity: AA 1-376

Specificity: Recognizes human FLIP (1-376aa).

Purification: Immunoaffinity purified

Immunogen: Recombinant human FLIP protein, expressed in E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG3 kappa

Application Details

Application Notes: Approved: ELISA (1:500), WB (1:500 - 1:1000)

Usage: Suitable for use in ELISA and Western Blot. ELISA: 1:500. Western Blot: 1:500-1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades