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Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity).
Subcellular location: Secreted
Synonyms: BNP, Bnf, Natriuretic peptides B, Gamma-brain natriuretic peptide, Iso-ANP, Nppb