GABA antibody

Catalog No. ABIN679013

Product Details anti-GABA Antibody

Target: GABA (gamma-Aminobutyric Acid (GABA))

Reactivity: Please inquire

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Cross-Reactivity (Details): GABA

Purification: Purified by Protein A.

Immunogen: KLH conjugated GABA

Isotype: IgG

Application Details

Application Notes: IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GABA antibody (ABIN679013)

Luo, Guo, Fan, Lu, Chen, Wang, Shao, Wu, Xu, Lü: "Niche astrocytes promote the survival, proliferation and neuronal differentiation of co-transplanted neural stem cells following ischemic stroke in rats." in: Experimental and therapeutic medicine, Vol. 13, Issue 2, pp. 645-650, (2017) (PubMed).

Target Details for GABA

Target: GABA (gamma-Aminobutyric Acid (GABA))

Alternative Name: Gaba (GABA Products)

Target Type: Amino Acid

Background:

Synonyms: gamma-aminobutyric acid, gamma aminobutyric acid, 4 aminobutanoic acid, GABA, Gamma amino butyric acid.

Background: Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABA acts at inhibitory synapses in the brain and spinal cord. Inhibition is provoked by GABA binding resulting in hyperpolarization of the synaptic transmembrane potential of the affected neuron. GABA binding causes ion channels to open allowing either the flow of chloride or potassium ions into or out of the cell.