beta 2 Adrenergic Receptor antibody (pSer346) (FITC)

Catalog No. ABIN682730

The Rabbit Polyclonal anti-beta 2 Adrenergic Receptor antibody is suitable to detect beta 2 Adrenergic Receptor in samples from Human. It has been validated for IF (cc) and IF (p).

Quick Overview for beta 2 Adrenergic Receptor antibody (pSer346) (FITC) (ABIN682730)

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta 2 Adrenergic Receptor antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-beta 2 Adrenergic Receptor Antibody (FITC)

Binding Specificity: pSer346

Purpose: phospho-ADRB2 (Ser346) Polyclonal Antibody, FITC Conjugated

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser346

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Alternative Name: ADRB2

Background:

Synonyms: BAR, B2AR, ADRBR, ADRB2R, BETA2AR, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2

Background: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gene ID: 154

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation