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BAX antibody (pSer184) (Cy5)

The Rabbit Polyclonal anti-BAX antibody has been validated for WB and FACS. It is suitable to detect BAX in samples from Human, Mouse and Rat.
Catalog No. ABIN682847

Quick Overview for BAX antibody (pSer184) (Cy5) (ABIN682847)

Target

See all BAX Antibodies
BAX (BCL2-Associated X Protein (BAX))

Reactivity

  • 238
  • 152
  • 135
  • 46
  • 32
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Human, Mouse, Rat

Host

  • 158
  • 96
  • 3
  • 1
Rabbit

Clonality

  • 168
  • 90
Polyclonal

Conjugate

  • 136
  • 13
  • 11
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  • 5
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  • 2
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This BAX antibody is conjugated to Cy5

Application

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Western Blotting (WB), Flow Cytometry (FACS)
  • Binding Specificity

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    pSer184

    Cross-Reactivity

    Human, Mouse, Rat

    Predicted Reactivity

    Dog,Cow,Sheep,Pig

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184

    Isotype

    IgG
  • Application Notes

    FCM 1:20-100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    BAX (BCL2-Associated X Protein (BAX))

    Alternative Name

    Bax

    Background

    Synonyms: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX

    Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    Molecular Weight

    21kDa

    Gene ID

    581

    UniProt

    Q07812

    Pathways

    p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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