Ghrelin antibody (AA 24-51) (Biotin)

Catalog No. ABIN685659

Product Details anti-Ghrelin Antibody (Biotin)

Target: Ghrelin (GHRL)

Binding Specificity: AA 24-51

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ghrelin antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide of mouse Ghrelin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Ghrelin

Target: Ghrelin (GHRL)

Alternative Name: Ghrelin 28 (GHRL Products)

Synonyms: 2210006E23Rik antibody, Ghr antibody, MTLRP antibody, MTLRPAP antibody, m46 antibody, Gh1-1 antibody, GRHL antibody, MTLRP-AP antibody, GHR antibody, ghrelin antibody, ghrelin and obestatin prepropeptide antibody, ghrelin/obestatin prepropeptide antibody, Ghrl antibody, GHRL antibody, ghrl antibody

Background:

Synonyms: Appetite-regulating hormone, growth hormone secretagogue, growth hormone-releasing peptide, motilin-related peptide, protein M46, grehlin

Background: Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Also known as Appetite regulating hormone, GHRL, Growth hormone releasing peptide, Growth hormone secretagogue, M46 protein, Motilin related peptide, MTLRP, Obestatin, Obestatin preprohormone, PRO1066, UNQ524. Sequence notes: Gly-Ser-Ser-Phe-Leu-Ser-Pro- Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu- Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg (mo, rat)

Gene ID: 58991

UniProt: Q9EQX0

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour