LIFR antibody (AA 451-580)

Catalog No. ABIN686827

This Rabbit Polyclonal antibody specifically detects LIFR in WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for LIFR antibody (AA 451-580) (ABIN686827)

Target: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LIFR Antibody

Binding Specificity: AA 451-580

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat LIFR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LIFR antibody (ABIN686827)

Murphy, Halow, Royer, Hennebold: "Leukemia Inhibitory Factor Is Necessary for Ovulation in Female Rhesus Macaques." in: Endocrinology, Vol. 157, Issue 11, pp. 4378-4387, (2016) (PubMed).

Target Details for LIFR

Target: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Alternative Name: Lifr/Cd118

Background:

Synonyms: SWS, SJS2, STWS, CD118, LIF-R, Leukemia inhibitory factor receptor, LIF receptor, LIFR

Background: Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

Gene ID: 3977

UniProt: O70535

Pathways: JAK-STAT Signaling, Growth Factor Binding