Integrin Alpha2b antibody

Catalog No. ABIN6937578

The Mouse Monoclonal anti-Integrin Alpha2b antibody has been validated for FACS and IF. It is suitable to detect Integrin Alpha2b in samples from Human.

Quick Overview for Integrin Alpha2b antibody (ABIN6937578)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: ITGA2B-1036

Product Details anti-Integrin Alpha2b Antibody

Specificity: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/ 3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human Integrin alpha IIb protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: KG1a, HEL cells and human platelets in lymph nodes or tonsils.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B

Background: BDPLT16, BDPLT2, GPalpha IIb, GT, HPA3, Integrin alpha IIb, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex,CD41a / Integrin-b (Platelet Marker)
Cellular localisation: Cell Surface

Molecular Weight: 90kDa

Gene ID: 3674, 411312

UniProt: P08514

Pathways: Integrin Complex