Recombinant KRT6A antibody
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- Target See all KRT6A Antibodies
- KRT6A (Keratin 6A (KRT6A))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This KRT6A antibody is un-conjugated
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human Cytokeratin 6A (KRT6A) protein
- Clone
- RKRT6A-2100
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product KRT6A Primary Antibody
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- Application Notes
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Tonsil or basal cell carcinoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- KRT6A (Keratin 6A (KRT6A))
- Alternative Name
- KRT6A (KRT6A Products)
- Synonyms
- CK6A antibody, CK6C antibody, CK6D antibody, K6A antibody, K6C antibody, K6D antibody, KRT6C antibody, KRT6D antibody, 2310016L08Rik antibody, Krt2-6a antibody, Krt2-6c antibody, MK6a antibody, mK6[a] antibody, CK-6A antibody, Krt6a antibody, KRT6A antibody, keratin 6A antibody, similar to keratin complex 2, basic, gene 6a antibody, keratin, type II cytoskeletal 6A antibody, KRT6A antibody, Krt6a antibody, LOC683313 antibody, LOC101112304 antibody
- Background
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58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5,Cytokeratin 6A (KRT6A) (Basal Cell Marker)
Cellular localisation: Cytoplasmic - Molecular Weight
- 58kDa
- Gene ID
- 3853, 700779
- UniProt
- P02538
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