ODC1 antibody

Catalog No. ABIN6938102

Product Details anti-ODC1 Antibody

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ODC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Cross-Reactivity (Details): Human. Mouse. Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ODC-1 protein

Clone: ODC1-485

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Western Blot (0.5-1 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: PC3 or LNCaP cells. Placental tissue lysate. Placenta, Prostate or Testicular carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Alternative Name: ODC1 (ODC1 Products)

Synonyms: CG8721 antibody, Dmel\\CG8721 antibody, dodc1 antibody, odc antibody, fc54f04 antibody, fi06d08 antibody, CHUNP6922 antibody, wu:fc54f04 antibody, wu:fi06d08 antibody, odc2 antibody, xODC1 antibody, xodc2 antibody, DDBDRAFT_0204020 antibody, DDBDRAFT_0237755 antibody, DDB_0204020 antibody, DDB_0237755 antibody, ODC antibody, odc1 antibody, ODC1 antibody, Odc antibody, odc1-a antibody, Ornithine decarboxylase 1 antibody, ornithine decarboxylase 1 antibody, ornithine decarboxylase antibody, diaminopimelate decarboxylase antibody, Orn/DAP/Arg decarboxylase 2 domain-containing protein antibody, Diaminopimelate decarboxylase antibody, Ornithine decarboxylase antibody, ornithine decarboxylase 1 L homeolog antibody, ornithine decarboxylase, structural 1 antibody, Odc1 antibody, odc1 antibody, ODC1 antibody, odc antibody, RR_RS04895 antibody, ASA_RS06380 antibody, LOC100232922 antibody, odc1.L antibody, odc-1 antibody

Background: Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
Cellular localisation: Cytoplasmic

Molecular Weight: 53kDa

Gene ID: 4953, 467701

UniProt: P11926