Recombinant Uroplakin 1B antibody (AA 109-229)

Catalog No. ABIN7857623

This Rabbit Monoclonal antibody specifically detects Uroplakin 1B in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant Uroplakin 1B antibody (AA 109-229) (ABIN7857623)

Target: Uroplakin 1B (UPK1B)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: UPK1B-9258R

Product Details anti-Uroplakin 1B Antibody

Binding Specificity: AA 109-229

Expression System: CHO Cells

Purpose: Recombinant Uroplakin 1B (Urothelial Differentiation Marker) Antibody

Specificity: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: Uroplakin 1B

Background:

Tetraspanin-20, Tspan-20, TSPAN20, UP1b, UPIb, UPK1B, Uroplakin-1b

Urinary bladder (IHC).

Molecular Weight: 30kDa

Gene ID: 7348, 271580

UniProt: O75841