Integrin Alpha2b antibody

Catalog No. ABIN6939801

This Mouse Monoclonal antibody specifically detects Integrin Alpha2b in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for Integrin Alpha2b antibody (ABIN6939801)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: ITGA2B-1036

Product Details anti-Integrin Alpha2b Antibody

Specificity: Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/ 3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length human Integrin alpha IIb protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: KG1a, HEL cells and human platelets in lymph nodes or tonsils.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B

Molecular Weight: 90kDa

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex