CALB1 antibody (AA 7-96)

Catalog No. ABIN6940930

Product Details anti-CALB1 Antibody

Target: CALB1 (Calbindin (CALB1))

Binding Specificity: AA 7-96

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CALB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogen: Recombinant fragment (around aa 7-96) of human CALB1 protein (exact sequence is proprietary)

Clone: CALB1-3333

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.

Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CALB1

Target: CALB1 (Calbindin (CALB1))

Alternative Name: CALB1 (CALB1 Products)

Synonyms: CALB antibody, CG6702 antibody, Calb antibody, Cbp33 antibody, DCBP antibody, Dcbp antibody, Dcp antibody, Dmel\\CG6702 antibody, cbn antibody, cbp53E antibody, Calbindin antibody, CB antibody, Calb-1 antibody, Brain-2 antibody, CaBP28K antibody, calb1 antibody, CALB1 antibody, fj53a05 antibody, wu:fj53a05 antibody, calbindin 1 antibody, Calbindin 53E antibody, CALB1 antibody, Cbp53E antibody, Calb1 antibody, calb1 antibody

Background: The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 and , Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin and Parvalbumin (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

Molecular Weight: 52kDa

Gene ID: 793

UniProt: P05937