CD22 antibody
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- Target See all CD22 Antibodies
- CD22 (CD22 Molecule (CD22))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD22 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunomicroscopy (IM)
- Specificity
- Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
- Purification
- Purified by Protein A/G
- Immunogen
- Human Raji cells
- Clone
- MYG13
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD22 Primary Antibody
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anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reactivity: Human FACS, WB, ELISA, IHC, ICC Host: Mouse Monoclonal 2H1C4 unconjugated
anti-CD22 Molecule (CD22) (AA 621-725) antibodyCD22 Reactivity: Human FACS, WB, ELISA, ICC Host: Mouse Monoclonal 1A3A11 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivity: Human FACS, WB, ELISA, IHC, IF, Coat, StM Host: Mouse Monoclonal BLCAM-1795 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivity: Human FACS, WB, ELISA, IHC, IF, Coat Host: Mouse Monoclonal BLCAM-1796 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivity: Human, Non-Human Primate FACS, WB, IP Host: Mouse Monoclonal MEM-01 unconjugated
anti-CD22 Molecule (CD22) antibody (PE)CD22 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal MEM-01 PE
anti-CD22 Molecule (CD22) antibody (FITC)CD22 Reactivity: Human FACS Host: Mouse Monoclonal IS7 FITC
anti-CD22 Molecule (CD22) antibodyCD22 Reactivity: Human, Mouse, Rat, Monkey, Dog WB, IHC, IHC (p) Host: Mouse Monoclonal 4C3 unconjugated
anti-CD22 Molecule (CD22) (AA 708-847) antibodyCD22 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivity: Human IHC Host: Rabbit Monoclonal MSVA-022R unconjugated Recombinant Antibody
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- Application Notes
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Positive Control: Ramos, Raji, Daudi, IM9, JY25 and human peripheral blood lymphocytes. Human tonsil and lymphocytes.
Known Application: Flow Cytometry (0.5-1 μg/million cells),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- CD22 (CD22 Molecule (CD22))
- Alternative Name
- CD22 (CD22 Products)
- Synonyms
- A530093D23 antibody, Lyb-8 antibody, Lyb8 antibody, SIGLEC-2 antibody, SIGLEC2 antibody, siglec-2 antibody, CD22 antigen antibody, CD22 molecule antibody, Cd22 antibody, CD22 antibody
- Molecular Weight
- 130-140kDa
- Gene ID
- 933
- UniProt
- P20273
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