IL-6 antibody

Catalog No. ABIN6941475

The Rat Monoclonal anti-IL-6 antibody (Clone MP5-20F3) (ABIN6941475) specifically detects IL-6 in FACS, Neut and IF. The antibody is reactive with Mouse samples.

Quick Overview for IL-6 antibody (ABIN6941475)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Neutralization (Neut), Immunofluorescence (IF)

Clone: MP5-20F3

Product Details anti-IL-6 Antibody

No Cross-Reactivity: Human, Rat (Rattus)

Purification: Purified by Protein A/G

Immunogen: Recombinant Mouse IL-6 protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Mouse heart.

Known Application: Neutralization Studies (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL-6 (Interleukin-6)

Background: IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.

Molecular Weight: 21kDa

Gene ID: 16193

UniProt: P08505

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome