AKT2 antibody (AA 21-120) (Biotin)

Catalog No. ABIN6942064

The Rabbit Polyclonal anti-AKT2 antibody is suitable to detect AKT2 in samples from Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for AKT2 antibody (AA 21-120) (Biotin) (ABIN6942064)

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKT2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AKT2 Antibody (Biotin)

Binding Specificity: AA 21-120

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKT2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for AKT2

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Alternative Name: AKT2

Background:

Synonyms: C AKT, MGC9965, Oncogene AKT1, PKB, PRKBA, Protein Kinase B Alpha, RAC, RAC PK Alpha, RAC Serine/Threonine Protein Kinase, vAKT Murine Thymoma Viral Oncogene Homolog 1, AKT2_HUMAN, HIHGHH, AKT 2, AKT-2, Akt2, PKB beta, PKB-beta, PKBB, PKBBETA, PRKBB, Protein kinase Akt 2, Protein kinase Akt-2, Protein kinase B beta, RAC BETA, RAC beta serine threonine protein kinase, RAC PK beta, Rac protein kinase beta, Rac protein kinase beta, RAC-BETA, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, V AKT Murine Thymoma Viral Oncogene Homolog 2.

Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008].

Gene ID: 208

UniProt: P31751

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling