Recombinant ICAM1 antibody (AA 1-100)

Catalog No. ABIN6943765

The Rabbit Monoclonal anti-ICAM1 antibody is suitable to detect ICAM1 in samples from Human. It has been validated for WB, IHC (p), IHC (fro) and IF (p).

Quick Overview for Recombinant ICAM1 antibody (AA 1-100) (ABIN6943765)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ICAM1 Antibody

Binding Specificity: AA 1-100

Purpose: ICAM1 Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant human ICAM1 between 1-100 amino acids

Isotype: IgG

Application Details

Application Notes: WB(WB(1:1000-5000)), IHC-P(IHC-P(1:200-1000)), IHC-F(IHC-F(1:200-1000)), IF(IHC-P)(IF(IHC-P)(1:200-1000))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM1

Background:

Synonyms: Intercellular adhesion molecule 1, Major group rhinovirus receptor, CD_antigen: CD54, ICAM-1, ICAM1

Background: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Gene ID: 3383

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling