IDE antibody (C-Term)

Catalog No. ABIN6943805

The Rabbit Monoclonal anti-IDE antibody (Clone 3C9) (ABIN6943805) specifically detects IDE in WB, IHC, IHC (p) and IF (cc). The antibody is reactive with Human, Mouse, Rat and Zebrafish (Danio rerio) samples.

Quick Overview for IDE antibody (C-Term) (ABIN6943805)

Target: IDE (Insulin-Degrading Enzyme (IDE))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IDE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 3C9

Product Details anti-IDE Antibody

Binding Specificity: C-Term

Purpose: Insulin degrading enzyme (3C9) Monoclonal Antibody

Cross-Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio)

Purification: Purified by Protein A.

Immunogen: Human Insulin degrading enzyme aa 950 to the C-terminus

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:50-200), IF(ICC)(1:50-200), IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IDE

Target: IDE (Insulin-Degrading Enzyme (IDE))

Alternative Name: Insulin degrading enzyme

Background:

Synonyms: Insulin-degrading enzyme, Abeta-degrading protease, Insulin protease, Insulysin, Insulinase, IDE

Background: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Gene ID: 3416

UniProt: P14735

Pathways: SARS-CoV-2 Protein Interactome