Laminnin 5 alpha 3 antibody
Reactivity: Human
IF (cc), WB
Host: Rabbit
Monoclonal
8C1
unconjugated
-
- Target
- Laminnin 5 alpha 3
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Monoclonal
- Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- Human Laminnin 5 alpha 3 aa 1600-1800
- Clone
- 8C1
- Isotype
- IgG
-
- Application Notes
-
WB 1:300-5000
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- Laminnin 5 alpha 3
- Background
-
Synonyms: Laminin subunit alpha-3, Epiligrin 170 kDa subunit, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha, E170, LAMA3
Background: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
- Gene ID
- 3909
- UniProt
- Q16787
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