MAPRE3 antibody

Catalog No. ABIN6944011

Product Details anti-MAPRE3 Antibody

Target: MAPRE3 (Microtubule-Associated Protein, RP/EB Family, Member 3 (MAPRE3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MAPRE3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human EB3 1-150

Clone: 3C9

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAPRE3

Target: MAPRE3 (Microtubule-Associated Protein, RP/EB Family, Member 3 (MAPRE3))

Alternative Name: MAPRE3 (MAPRE3 Products)

Synonyms: EB3 antibody, EBF3 antibody, EBF3-S antibody, RP3 antibody, AI790651 antibody, EB2 antibody, MGC68667 antibody, zgc:114065 antibody, fj35g02 antibody, wu:fj35g02 antibody, zgc:91952 antibody, microtubule associated protein RP/EB family member 3 antibody, microtubule-associated protein, RP/EB family, member 3 antibody, microtubule associated protein RP/EB family member 3 S homeolog antibody, microtubule-associated protein, RP/EB family, member 3a antibody, microtubule-associated protein, RP/EB family, member 3b antibody, MAPRE3 antibody, Mapre3 antibody, mapre3.S antibody, mapre3a antibody, mapre3b antibody

Background:

Synonyms: Microtubule-associated protein RP/EB family member 3, EB1 protein family member 3, End-binding protein 3, RP3, EBF3, EB3, MAPRE3, MARE3_HUMAN.

Background: Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules. May play a role in cell migration

Gene ID: 22924

UniProt: Q9UPY8