P2RY6 antibody

Catalog No. ABIN6944380

Product Details anti-P2RY6 Antibody

Target: P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This P2RY6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic peptide corresponding to N-terminal human P2Y6.

Clone: 8H2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P2RY6

Target: P2RY6 (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6 (P2RY6))

Alternative Name: P2Y6 (P2RY6 Products)

Synonyms: P2Y6 antibody, 2010204J23Rik antibody, P2y6 antibody, P2RY3 antibody, P2Y3 antibody, P2Y6R antibody, pyrimidinergic receptor P2Y6 antibody, pyrimidinergic receptor P2Y, G-protein coupled, 6 antibody, P2RY6 antibody, P2ry6 antibody

Background:

Synonyms: P2Y purinoceptor 6, P2Y6, P2RY6

Background: P2Y6 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Gene ID: 5031

UniProt: Q15077

Pathways: Smooth Muscle Cell Migration