PAX6 antibody
Quick Overview for PAX6 antibody (ABIN6944444)
Target
See all PAX6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- Human PAX6 between 250 to 350 amino acids
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC() -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- PAX6 (Paired Box 6 (PAX6))
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Alternative Name
- PAX6
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Background
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Synonyms: Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6
Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
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UniProt
- P26367
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Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
Target
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