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PAX6 antibody

This anti-PAX6 antibody is a Rabbit Monoclonal antibody detecting PAX6 in WB, FACS, IHC and IHC (p). Suitable for Human, Mouse and Rat.
Catalog No. ABIN6944444

Quick Overview for PAX6 antibody (ABIN6944444)

Target

See all PAX6 Antibodies
PAX6 (Paired Box 6 (PAX6))

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This PAX6 antibody is un-conjugated

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

8T3
  • Cross-Reactivity

    Human, Mouse, Rat

    Purification

    Purified by Protein A.

    Immunogen

    Human PAX6 between 250 to 350 amino acids

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC()

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    PAX6 (Paired Box 6 (PAX6))

    Alternative Name

    PAX6

    Background

    Synonyms: Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6

    Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

    UniProt

    P26367

    Pathways

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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