PAX6 antibody (Paired Box 6)

Details for Product anti-PAX6 Antibody No. ABIN6944444
Antigen
  • pax6
  • an2
  • mgda
  • wagr
  • pax-6
  • pax6a
  • xpax6
  • XLPAX6
  • MGC52531
  • PAX-6
  • AN
  • AN2
  • D11S812E
  • MGDA
  • WAGR
  • Pax-6
  • pax6b
  • 1500038E17Rik
  • AEY11
  • Dey
  • Gsfaey11
  • Sey
  • PAXZF-A
  • Pax6.1
  • cb280
  • fc20e07
  • pax-a
  • pax[zf-a]
  • paxzfa
  • wu:fc20e07
  • zfpax-6a
  • zfpax-6b
  • paired box 6
  • paired box 6 L homeolog
  • paired box 6 S homeolog
  • paired box 6a
  • PAX6
  • pax6
  • Pax6
  • pax6.L
  • pax6.S
  • pax6a
Reactivity
Human, Mouse (Murine), Rat (Rattus)
250
120
113
35
10
7
6
5
5
5
4
3
3
2
1
1
1
1
1
Host
Rabbit
149
113
8
Clonality (Clone)
Monoclonal ()
Conjugate
This PAX6 antibody is un-conjugated
12
10
9
9
9
8
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
196
105
99
82
63
24
22
21
13
7
5
4
4
3
2
2
1
Options
Immunogen Human PAX6 between 250 to 350 amino acids
Clone 8T3
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PAX6 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PAX6 (PAX6 Antibody Abstract)
Background

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.


Synonyms: Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6
UniProt P26367
Pathways Peptide Hormone Metabolism, Carbohydrate Homeostasis
Application Notes WB(1:300-1000), FCM(1:20-100), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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