PDIA6 antibody (Protein Disulfide Isomerase Family A, Member 6)

Details for Product anti-PDIA6 Antibody No. ABIN6944473
Antigen
  • 1700015E05Rik
  • AL023058
  • C77895
  • CaBP5
  • P5
  • Txndc7
  • ERP5
  • TXNDC7
  • CaBP1
  • pdi-p5
  • erp5
  • pdia6
  • pdip5
  • txndc7
  • protein disulfide isomerase family A member 6
  • protein disulfide isomerase associated 6
  • protein disulfide isomerase family A, member 6
  • protein disulfide isomerase family A member 6 L homeolog
  • PDIA6
  • Pdia6
  • pdia6.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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35
31
4
4
4
3
3
3
1
1
1
Host
Rabbit
48
7
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PDIA6 antibody is un-conjugated
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
49
22
13
10
9
7
6
3
2
2
2
1
1
Options
Immunogen Human PDIA6 between 300 to 500 amino acids
Clone 4C3
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PDIA6 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PDIA6 (PDIA6 Antibody Abstract)
Background

May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).


Synonyms: Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7, ER protein 5, ERp5, PDIA6
Gene ID 10130
UniProt Q15084
Pathways ER-Nucleus Signaling, Cell RedoxHomeostasis
Application Notes WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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