PKC delta antibody (Protein Kinase C, delta)

Details for Product anti-PKCd Antibody No. ABIN6944554
Antigen
  • MAY1
  • PKCD
  • nPKC-delta
  • AI385711
  • D14Ertd420e
  • PKC[d]
  • PKCdelta
  • Pkcd
  • fb09d10
  • fv43b11
  • prkcd
  • wu:fb09d10
  • wu:fv43b11
  • zgc:56558
  • PKC-delta
  • may1
  • npkc-delta
  • pkc-delta2
  • pkcd
  • tpa-1
  • protein kinase C delta
  • protein kinase C, delta
  • protein kinase C, delta a
  • protein kinase C delta L homeolog
  • PRKCD
  • Prkcd
  • prkcda
  • prkcd.L
  • prkcd
Reactivity
Human, Mouse (Murine), Rat (Rattus)
323
171
152
15
6
4
4
4
3
3
2
Host
Rabbit
329
24
Clonality (Clone)
Monoclonal ()
Conjugate
This PKC delta antibody is un-conjugated
17
10
10
10
10
10
10
7
5
5
5
4
1
1
1
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Western Blotting (WB)
264
143
129
40
31
18
15
14
11
6
5
2
2
1
1
1
1
Options
Immunogen Mouse PKC delta aa 500 to the C-terminus
Clone 2C4
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PKC delta products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PKC delta (PKCd Antibody Abstract)
Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].


Synonyms: Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, PRKCD
Gene ID 5580
UniProt Q05655
Pathways Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
Application Notes WB(1:300-1000), IF(ICC)(1:50-200), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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