CPT1A antibody (AA 351-450) (Biotin)

Catalog No. ABIN6945105

This Rabbit Polyclonal antibody specifically detects CPT1A in WB, ELISA and IHC (p). It exhibits reactivity toward Mouse, Rat and Pig.

Quick Overview for CPT1A antibody (AA 351-450) (Biotin) (ABIN6945105)

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Reactivity: Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPT1A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CPT1A Antibody (Biotin)

Binding Specificity: AA 351-450

Cross-Reactivity: Mouse, Pig, Rat

Predicted Reactivity: Human,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CPT1A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CPT1A

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Alternative Name: CPT1A

Background:

Synonyms: CPT 1, CPT1A, CPTI-L, CPT1-L, carnitine palmitoyl transferase 1, Carnitine O-palmitoyltransferase 1, liver isoform, CPT I, Carnitine palmitoyltransferase 1A, carnitine O-palmitoyltransferase 1, liver isoform isoform 1, CPT1A_HUMAN.

Background: The mitochondrial oxidation of long-chain fatty acids is nitiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 1374

UniProt: P50416

Pathways: AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process