DAZ2 antibody (AA 51-150) (Biotin)

Catalog No. ABIN6942812

This anti-DAZ2 antibody is a Rabbit Polyclonal antibody detecting DAZ2 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for DAZ2 antibody (AA 51-150) (Biotin) (ABIN6942812)

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DAZ2 Antibody (Biotin)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAZ2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DAZ2

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Alternative Name: DAZ2

Background:

Synonyms: DAZ2, DAZ2_HUMAN, DAZ3, Deleted in azoospermia 2, Deleted in azoospermia protein 2, Deleted in azoospermia protein 3, MGC126442, pDP1678, DAZ1, DAZ4, DAZL

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Gene ID: 57055

UniProt: Q13117