DNAI1 antibody

Catalog No. ABIN6943024

Product Details anti-DNAI1 Antibody

Target: DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))

Reactivity: Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DNAI1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: Human Dynein intermediate chain 1 aa 1-200

Clone: 3A1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNAI1

Target: DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))

Alternative Name: DNAI1 (DNAI1 Products)

Synonyms: CILD1 antibody, DIC1 antibody, ICS1 antibody, PCD antibody, 1110066F04Rik antibody, BB124644 antibody, Dnai1 antibody, b2b1526Clo antibody, Dnaic1 antibody, dynein axonemal intermediate chain 1 antibody, dynein, axonemal, intermediate chain 1 antibody, DNAI1 antibody, Dnaic1 antibody, Dnai1 antibody

Background:

Synonyms: Dynein intermediate chain 1 axonemal, Axonemal dynein intermediate chain 1, DNAI1, CILD1.

Background: This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.

Gene ID: 27019

UniProt: Q9UI46