IL-6 antibody

Catalog No. ABIN6964024

Cited in 1 publication. The Rat Monoclonal anti-IL-6 antibody (Clone 13A5) (ABIN6964024) specifically detects IL-6 in Neut. The antibody is reactive with Human and Non-Human Primate samples.

Quick Overview for IL-6 antibody (ABIN6964024)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivity: Human, Non-Human Primate

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-6 antibody is un-conjugated

Application: Neutralization (Neut)

Clone: 13A5

Product Details anti-IL-6 Antibody

Specificity: Native and recombinant IL-6

Cross-Reactivity (Details): The antibody cross-reacts with IL-6 from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-6

Isotype: IgG1

Application Details

Application Notes: Neutralization of human IL-6 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-6 antibody (ABIN6964024)

Barrionuevo, Cassataro, Delpino, Zwerdling, Pasquevich, García Samartino, Wallach, Fossati, Giambartolomei: "Brucella abortus inhibits major histocompatibility complex class II expression and antigen processing through interleukin-6 secretion via Toll-like receptor 2." in: Infection and immunity, Vol. 76, Issue 1, pp. 250-62, (2008) (PubMed).

Target Details for IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Alternative Name: IL6

Gene ID: 3569

Pathways: TLR Signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome