GLIS1 antibody (N-Term)

Catalog No. ABIN6971686

Product Details anti-GLIS1 Antibody

Target: GLIS1 (GLIS Family Zinc Finger 1 (GLIS1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This GLIS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: GLIS1 (Glis Family Zinc Finger 1) belongs to a GLIS subfamily of Krüppel-like zinc-finger transcription factors characterized to regulate a set of downstream targets essential for cellular functions, including pancreatic development, b-cell maturation and maintenance, and insulin production. GLIS1 is enriched in unfertilized eggs and embryos and it can be used to promote direct reprogramming of somatic cells to induced pluripotent stem cells (iPS cells). GLIS1 may regulate the expression of numerous genes, either positively or negatively, and is implicated in mitral valve development, where dysregulation may lead to mitral valve prolapse (MVP). GLIS1 antibody (mAb) (Clone 7-14) was raised in a Rat host. It has been validated for use in Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Protein G Chromatography

Immunogen: This antibody was raised against a peptide within the amino-terminal half of human GLIS1 (GLI-similar 1), which shares homology with mouse GLIS1.

Clone: 7-14

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for GLIS1

Target: GLIS1 (GLIS Family Zinc Finger 1 (GLIS1))

Alternative Name: GLIS1 (GLIS1 Products)

Synonyms: GLIS1 antibody, Gli5 antibody, Gli6 antibody, GliH1 antibody, GLIS family zinc finger 1 antibody, Glis1 antibody, GLIS1 antibody, glis1 antibody

Molecular Weight: 95 kDa

NCBI Accession: NP_671726