HSC70 / HSP7C antibody
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- Target
- HSC70 / HSP7C
- Reactivity
- Human
- Host
- Rat
- Clonality
- Monoclonal
- Application
- Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
- Characteristics
- HSC70 / HSP7C (Heat Shock Cognate 70, HSP73, Heat Shock Protein 73) is a member of the DnaK/HSP70 family of protein chaperones involved in protein homeostasis. HSC70 is constitutively expressed and essential for cell viability and functions both in preventing or reversing protein aggregation and in disassembling protein complexes. HSC70 predominantly binds non-native polypeptides and folding intermediates that are either newly synthesized or stress-induced. HSC70 / HSP7C antibody (mAb) (Clone 6E1) was raised in a Rat host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot, it has been shown to react with Human samples.
- Purification
- Protein G Chromatography
- Immunogen
- This HSC70 / HSP7C antibody was raised against full-length recombinant human HSC70 / HSP7C protein.
- Clone
- 6E1
- Isotype
- IgG2a
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- Target
- HSC70 / HSP7C
- Molecular Weight
- 70 kDa
- NCBI Accession
- NP_006588
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