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HSC70 / HSP7C antibody

Reactivity: Human ICC, IF, IP, WB Host: Rat Monoclonal 6E1 unconjugated
Catalog No. ABIN6972179
  • Target
    HSC70 / HSP7C
    Reactivity
    Human
    Host
    Rat
    Clonality
    Monoclonal
    Application
    Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
    Characteristics
    HSC70 / HSP7C (Heat Shock Cognate 70, HSP73, Heat Shock Protein 73) is a member of the DnaK/HSP70 family of protein chaperones involved in protein homeostasis. HSC70 is constitutively expressed and essential for cell viability and functions both in preventing or reversing protein aggregation and in disassembling protein complexes. HSC70 predominantly binds non-native polypeptides and folding intermediates that are either newly synthesized or stress-induced. HSC70 / HSP7C antibody (mAb) (Clone 6E1) was raised in a Rat host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot, it has been shown to react with Human samples.
    Purification
    Protein G Chromatography
    Immunogen
    This HSC70 / HSP7C antibody was raised against full-length recombinant human HSC70 / HSP7C protein.
    Clone
    6E1
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    HSC70 / HSP7C
    Molecular Weight
    70 kDa
    NCBI Accession
    NP_006588
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