NUDCD3 antibody (AA 161-260) (Alexa Fluor 350)

Catalog No. ABIN6976484

Product Details anti-NUDCD3 Antibody (Alexa Fluor 350)

Target: NUDCD3 (NudC Domain Containing 3 (NUDCD3))

Binding Specificity: AA 161-260

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUDCD3 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NUDCD3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NUDCD3

Target: NUDCD3 (NudC Domain Containing 3 (NUDCD3))

Alternative Name: NUDCD3 (NUDCD3 Products)

Synonyms: NudCL antibody, AI427847 antibody, BC024322 antibody, RP23-28G13.2 antibody, mKIAA1068 antibody, NudC domain containing 3 antibody, Nudcd3 antibody, NUDCD3 antibody

Background:

Synonyms: NudC domain-containing protein 3, NUDCD3, KIAA1068

Background: NUDCD3 functions to maintain the stability of dynein intermediate chain. Depletion of NUDCD3 results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. NUDCD3 levels increase after the G1/S transition.

Gene ID: 23386

UniProt: Q8IVD9