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NR3C2 antibody (AA 1-100) (AbBy Fluor® 594)

NR3C2 Reactivity: Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 594
Catalog No. ABIN6979522
  • Target See all NR3C2 Antibodies
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Binding Specificity
    • 16
    • 15
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 56
    • 42
    • 28
    • 17
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Rat
    Host
    • 66
    • 5
    Rabbit
    Clonality
    • 66
    • 5
    Polyclonal
    Conjugate
    • 24
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    This NR3C2 antibody is conjugated to AbBy Fluor® 594
    Application
    • 69
    • 38
    • 38
    • 20
    • 14
    • 12
    • 10
    • 9
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NR3C2/Mineralocorticoid receptor
    Isotype
    IgG
    Top Product
    Discover our top product NR3C2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Alternative Name
    NR3C2/Mineralocorticoid receptor (NR3C2 Products)
    Background

    Synonyms: Aldosterone receptor, MCR, MGC133092, MLR, MR, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2, MCR_HUMAN.

    Background: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

    Gene ID
    4306
    UniProt
    P08235
    Pathways
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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