Thrombomodulin antibody (AA 21-120) (AbBy Fluor® 750)

Catalog No. ABIN6982176

The AbBy Fluor® 750-conjugated Rabbit Polyclonal anti-Thrombomodulin antibody (ABIN6982176) specifically detects Thrombomodulin in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for Thrombomodulin antibody (AA 21-120) (AbBy Fluor® 750) (ABIN6982176)

Target: Thrombomodulin (THBD)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombomodulin antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Thrombomodulin Antibody (AbBy Fluor® 750)

Binding Specificity: AA 21-120

Purpose: Thrombomodulin Polyclonal Antibody, AbBy Fluor-750 Conjugated

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thrombomodulin

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: Thrombomodulin

Background:

Synonyms: Thrombomodulin, CD 141, CD141, CD141 antigen, Fetomodulin, THBD, THRM, TM, AHUS 6, AHUS6, BDCA 3, BDCA3, THPH12, TRBM_HUMAN

Background: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Gene ID: 7056

UniProt: P07204