SWAP70 antibody (AA 131-230) (Cy3)
Quick Overview for SWAP70 antibody (AA 131-230) (Cy3) (ABIN6983965)
Target
See all SWAP70 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 131-230
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Cross-Reactivity
- Human
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Predicted Reactivity
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human SWAP70
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Isotype
- IgG
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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Alternative Name
- SWAP70
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Background
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Synonyms: Switch-associated protein 70, SWAP70, SWAP70, KIAA0640, HSPC321
Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
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Gene ID
- 23075
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UniProt
- Q9UH65
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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