GRP78 antibody (Cy3)

Catalog No. ABIN6983995

This Mouse Monoclonal antibody specifically detects GRP78 in WB and IF (cc). It exhibits reactivity toward Human and Rat.

Quick Overview for GRP78 antibody (Cy3) (ABIN6983995)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRP78 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 12D9

Product Details anti-GRP78 Antibody (Cy3)

Cross-Reactivity: Human, Rat

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human GRP78/Bip

Isotype: IgG

Application Details

Application Notes: IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GRP78

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Alternative Name: GRP78/Bip

Background:

Synonyms: BIP, HSPA5, glucose regulated protein 78, 78 kDa glucose regulated protein, BIP, Endoplasmic reticulum lumenal Ca2+ binding protein grp78, FLJ26106, Glucose Regulated Protein 78 kDa, GRP 78, GRP78, Heat Shock 70 kDa Protein 5, HSPA 5, HSPA-5, HSPA5, Immunoglobulin Heavy Chain Binding Protein, MIF2, GRP78_HUMAN.

Background: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

Gene ID: 3309

UniProt: P11021

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling