BAX antibody (pSer184) (PE)
Quick Overview for BAX antibody (pSer184) (PE) (ABIN6988607)
Target
See all BAX AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer184
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Cross-Reactivity
- Human, Mouse, Rat
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Predicted Reactivity
- Dog,Cow,Sheep,Pig
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184
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Isotype
- IgG
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Application Notes
- FCM 1:20-100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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Alternative Name
- Bax
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Background
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Synonyms: BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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Gene ID
- 581
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UniProt
- Q07812
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Pathways
- p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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