PPP2R4 antibody (pTyr307)

Catalog No. ABIN6989930

The Rabbit Monoclonal anti-PPP2R4 antibody is suitable to detect PPP2R4 in samples from Human. It has been validated for WB, IHC, IP, IHC (p) and IF (cc).

Quick Overview for PPP2R4 antibody (pTyr307) (ABIN6989930)

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PPP2R4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 13B5

Product Details anti-PPP2R4 Antibody

Binding Specificity: pTyr307

Purpose: Phospho-PP2A(Y307) Monoclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic phospho-Peptide corresponding to residues surrounding Tyr307 of human PP2A.

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IF(ICC)(1:50-200), IP(1-2 μg), IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PPP2R4

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Alternative Name: PP2A

Background:

Synonyms: PP2A A antibody, PP2A alpha antibody, PP2A B antibody, PP2A beta antibody, PP2A-alpha antibody, PP2AA_HUMAN antibody, PP2Ac antibody, PP2CB antibody, PPP2CA antibody, PPP2CB antibody, Protein phosphatase 2 catalytic subunit alpha isoform antibody, Protein phosphatase 2 catalytic subunit beta isoform antibody, Replication protein C antibody, RP C antibody, RP-C antibody, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform antibody, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody

Background: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010].

Gene ID: 5515

UniProt: P62714

Pathways: PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades