ACE2 antibody

Catalog No. ABIN6989947

Product Details anti-ACE2 Antibody

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ACE2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Hamster, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within Human ACE2 aa 200-230.

Clone: 3B5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IP(1-2 μg)
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ACE2

Target: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Alternative Name: ACE2 (ACE2 Products)

Synonyms: ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody

Background:

Synonyms: ACE 2 antibody, ACE related carboxypeptidase antibody, ACE-related carboxypeptidase antibody, ACE2 antibody, ACE2_HUMAN antibody, ACEH antibody, Angiotensin converting enzyme 2 antibody, Angiotensin converting enzyme homolog antibody, Angiotensin converting enzyme like protein antibody, Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody, Angiotensin I converting enzyme 2 antibody, Angiotensin-converting enzyme homolog antibody, DKFZP434A014 antibody, EC 3.4.17 antibody, metalloprotease MPROT 15 antibody, Metalloprotease MPROT15 antibody, OTTHUMP00000022963 antibody, Processed angiotensin-converting enzyme 2 antibody

Background: Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension. ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus[10]. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.

Gene ID: 59272

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour