CDK7 antibody

Catalog No. ABIN6989957

The Rabbit Monoclonal anti-CDK7 antibody has been validated for WB, IHC, IHC (p), IF (cc) and FACS. It is suitable to detect CDK7 in samples from Human.

Quick Overview for CDK7 antibody (ABIN6989957)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Clone: 6G1

Product Details anti-CDK7 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Alternative Name: Cdk7

Background:

Synonyms: 39 kDa protein kinase antibody, CAK antibody, CAK1 antibody, Cdk activating kinase antibody, CDK-activating kinase 1 antibody, CDK-activating kinase antibody, cdk7 antibody, CDK7_HUMAN antibody, CDKN7 antibody, Cell division protein kinase 7 antibody, Cyclin dependent kinase 7 antibody, cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) antibody, Cyclin-dependent kinase 7 antibody, HCAK antibody, Homolog of Xenopus MO15 Cdk activating kinase antibody, Kinase subunit of CAK antibody, MO15 antibody, MO15, Xenopus, homolog of antibody, P39 Mo15 antibody, p39MO15 antibody, Serine threonine kinase Stk1 antibody, Serine/threonine protein kinase 1 antibody, Serine/threonine protein kinase MO15 antibody, STK1 antibody, TFIIH basal transcription factor complex kinase subunit antibody

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]

Gene ID: 1022

UniProt: P50613

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase