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SARS-CoV-2 NSP5 (3CL-Pro) antibody (N-Term)

3CL-PRO, M-Pro Reactivity: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990134
  • Target See all SARS-CoV-2 NSP5 (3CL-Pro) (3CL-PRO, M-Pro) Antibodies
    SARS-CoV-2 NSP5 (3CL-Pro) (3CL-PRO, M-Pro) (SARS-CoV-2 3C-Like Proteinase (NSP5) (3CL-PRO, M-Pro))
    Binding Specificity
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 3
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    Host
    • 3
    • 1
    Rabbit
    Clonality
    • 4
    Polyclonal
    Conjugate
    • 4
    This SARS-CoV-2 NSP5 (3CL-Pro) antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Anti-SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of SARS-CoV-2 (COVID-19) 3CL-Pro (NSP5) protein. The immunogen is located within the first 50 amino acids of the SARS-CoV-2 (COVID-19) 3CL-Pro (NSP5) protein.
    Isotype
    IgG
    Top Product
    Discover our top product 3CL-PRO, M-Pro Primary Antibody
  • Application Notes
    IHC: 0.5 μ,g/mL, WB: 0.5 μ,g/mL

    Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 NSP5 recombinant protein by ELISA and WB. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) antibody can be stored at 4 ° C for three months and -20 ° C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SARS-CoV-2 NSP5 (3CL-Pro) (3CL-PRO, M-Pro) (SARS-CoV-2 3C-Like Proteinase (NSP5) (3CL-PRO, M-Pro))
    Alternative Name
    SARS-CoV-2 3CL-PRO (3CL-PRO, M-Pro Products)
    Synonyms
    pp1ab antibody, ORF1a polyprotein;ORF1ab polyprotein antibody, ORF1ab antibody
    Target Type
    Viral Protein
    Background
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. 3C- like proteinase (NSP5) cleaves the C-terminus of replicase polyprotein at 11 sites (3,4,5). It recognizes substrates containing the core sequence [ILMVF]-Q-|-[SGACN]. It also able to bind an ADP-ribose-1''-phosphate (ADRP) (5).
    Gene ID
    43740578
    NCBI Accession
    YP_009742612
    UniProt
    P0DTC1
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