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TLR8 antibody (AA 790-840)

This anti-TLR8 antibody is a Rabbit Polyclonal antibody detecting TLR8 in WB, ELISA, ICC and IF. Suitable for Human and Mouse.
Catalog No. ABIN6990456

Quick Overview for TLR8 antibody (AA 790-840) (ABIN6990456)

Target

See all TLR8 Antibodies
TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivity

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Human, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This TLR8 antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Binding Specificity

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    AA 790-840

    Purification

    TLR8 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8. The immunogen is located within amino acids 790 - 840 of TLR8.

    Isotype

    IgG
  • Application Notes

    TLR8 antibody can be used for detection of TLR8 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    TLR8 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,4 °C

    Storage Comment

    TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    TLR8 (Toll-Like Receptor 8 (TLR8))

    Alternative Name

    TLR8

    Background

    TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.

    Molecular Weight

    Predicted: 112 kDa

    Observed: 107 kDa

    Gene ID

    51311

    NCBI Accession

    NP_619542

    UniProt

    Q9NR97

    Pathways

    TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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