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BOK antibody (N-Term)

BOK Reactivity: Human ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990478
  • Target See all BOK Antibodies
    BOK (BCL2-Related Ovarian Killer (BOK))
    Binding Specificity
    • 14
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 44
    • 12
    • 6
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 2
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 19
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BOK antibody is un-conjugated
    Application
    • 28
    • 27
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    At least three isoforms of BOK are known to exist, this antibody will not detect the smallest isoform. BOK antibody is predicted to not cross-react with other Bcl-2 protein family members
    Purification
    BOK Antibody is affinity chromatography purified via peptide column.
    Immunogen
    BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK. The immunogen is located within the first 50 amino acids of BOK.
    Isotype
    IgG
    Top Product
    Discover our top product BOK Primary Antibody
  • Application Notes
    BOK antibody can be used for detection of BOK by immunohistochemistry at 5 μ,g/mL.

    Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    BOK Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    BOK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    BOK (BCL2-Related Ovarian Killer (BOK))
    Alternative Name
    BOK (BOK Products)
    Synonyms
    BOK antibody, bok antibody, zgc:100979 antibody, zgc:64041 antibody, BCL2L9 antibody, BOKL antibody, Bok-BH3 antibody, AI847676 antibody, AU021146 antibody, matador antibody, mtd antibody, BOK, BCL2 family apoptosis regulator antibody, BCL2-related ovarian killer a antibody, BCL2-related ovarian killer b antibody, BCL2-related ovarian killer antibody, BOK antibody, boka antibody, bokb antibody, Bok antibody
    Background
    BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.
    Gene ID
    666
    UniProt
    Q9UMX3
    Pathways
    Positive Regulation of Endopeptidase Activity
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