SLITRK6 antibody (AA 250-300)

Catalog No. ABIN6990860

Product Details anti-SLITRK6 Antibody

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Binding Specificity: AA 250-300

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Purification: Slitrk6 Antibody is affinity chromatography purified via peptide column.

Immunogen: Slitrk6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human Slitrk6. The immunogen is located within amino acids 250 - 300 of Slitrk6.

Isotype: IgG

Application Details

Application Notes: Slitrk6 antibody can be used for detection of Slitrk6 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Slitrk6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Slitrk6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLITRK6

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Alternative Name: Slitrk6 (SLITRK6 Products)

Synonyms: 4832410J21Rik antibody, Sltk6 antibody, SLIT and NTRK like family member 6 antibody, SLIT and NTRK-like family, member 6 antibody, SLITRK6 antibody, slitrk6 antibody, Slitrk6 antibody

Background: Slitrk6 Antibody: SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.

Gene ID: 84189

UniProt: Q9H5Y7