ELOVL6 Antibody is affinity chromatography purified via peptide column.
Immunogen
ELOVL6 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ELOVL6. The immunogen is located within the first 50 amino acids of ELOVL6.
ELOVL6
Reactivity: Human
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
Cy5
Application Notes
ELOVL6 antibody can be used for detection of ELOVL6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
ELOVL6 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
ELOVL6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
FACE antibody, FAE antibody, LCE antibody, C77826 antibody, Lce2 antibody, rELO2 antibody, lce antibody, cb618 antibody, zgc:73089 antibody, elovl6 antibody, ELOVL fatty acid elongase 6 antibody, ELOVL family member 6, elongation of long chain fatty acids (yeast) antibody, elongation of very long chain fatty acids protein 6 antibody, elongation of very long chain fatty acids protein 6-like antibody, ELOVL6 antibody, Elovl6 antibody, elovl6 antibody, Tsp_06132 antibody, LOC108710167 antibody
Background
ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.