WNT10A antibody (C-Term)

Catalog No. ABIN6990921

Product Details anti-WNT10A Antibody

Target: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Binding Specificity: AA 300-350, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT10A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This Wnt10a antibody is predicted to not cross-react with Wnt10b.

Purification: Wnt10a Antibody is affinity chromatography purified via peptide column.

Immunogen: Wnt10a antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Wnt10a. The immunogen is located within amino acids 300 - 350 of Wnt10a.

Isotype: IgG

Application Details

Application Notes: Wnt10a antibody can be used for detection of Wnt10a by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Wnt10a Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Wnt10a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for WNT10A

Target: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Alternative Name: Wnt10a (WNT10A Products)

Synonyms: WNT10A antibody, wnt10a/12 antibody, wnt10a antibody, OODD antibody, SSPS antibody, STHAG4 antibody, WNT-10A antibody, Wnt family member 10A antibody, protein Wnt-10a antibody, Wnt10a protein antibody, hypothetical protein antibody, WNT10A protein antibody, Wnt family member 10A L homeolog antibody, wingless-type MMTV integration site family, member 10A antibody, wingless-type MMTV integration site family, member 10a antibody, WNT10A antibody, LOC778792 antibody, CpipJ_CPIJ005839 antibody, Wnt10a antibody, wnt10a antibody, wnt10a.L antibody

Background: Wnt10a Antibody: Wnt10a is a member of the Wnt family, a gene family that encodes secreted signaling proteins that play crucial roles in normal development such as regulation of cell fate and patterning during embryogenesis as well as neoplastic transformation. Elevated levels of Wnt10a have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia and it has been suggested that uncontrolled Wnt signaling may contribute to the defect in apoptosis that characterizes these malignancies. Recently, a mutation in Wnt10a was found to be associated with odonto-onycho-dermal dysplasia, an autosomal recessive ectodermal dysplasia.

Molecular Weight: Predicted: 46 kDa

Observed: 46 kDa

Gene ID: 80326

UniProt: Q9GZT5

Pathways: WNT Signaling