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NANOS2 antibody (C-Term)

NANOS2 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990923
  • Target See all NANOS2 Antibodies
    NANOS2 (Nanos Homolog 2 (NANOS2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 36
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 33
    • 3
    Rabbit
    Clonality
    • 35
    • 1
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NANOS2 antibody is un-conjugated
    Application
    • 24
    • 20
    • 4
    • 3
    • 2
    • 2
    ELISA, Western Blotting (WB)
    Specificity
    This Nanos2 antibody will not cross-react with either Nanos 1 or Nanos3.
    Purification
    Nanos2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Nanos2 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human Nanos2. The immunogen is located within the last 50 amino acids of Nanos2.
    Isotype
    IgG
    Top Product
    Discover our top product NANOS2 Primary Antibody
  • Application Notes
    Nanos2 antibody can be used for detection of Nanos2 by Western blot at 2 to 4 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Nanos2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    Nanos2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    NANOS2 (Nanos Homolog 2 (NANOS2))
    Alternative Name
    Nanos2 (NANOS2 Products)
    Synonyms
    NOS2 antibody, RGD1562436 antibody, nos2 antibody, nanos C2HC-type zinc finger 2 antibody, nanos homolog 2 (Drosophila) antibody, nanos 2 antibody, nanos2 protein antibody, NANOS2 antibody, Nanos2 antibody, nanos2 antibody
    Background
    Nanos2 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.
    Gene ID
    339345
    UniProt
    P60321
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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