Adenovirus 9 E4 Orf1 antibody (C-Term)

Catalog No. ABIN6990957

Product Details anti-Adenovirus 9 E4 Orf1 Antibody

Target: Adenovirus 9 E4 Orf1 (HAdV-9 E4-ORF1) (Human Adenovirus type 9 E4 Orf1 (HAdV-9 E4-ORF1))

Binding Specificity: C-Term

Reactivity: Human Adenovirus 9

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenovirus 9 E4 Orf1 antibody is un-conjugated

Application: ELISA

Purification: Adenovirus-9 E4 Orf1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Ad-9 E4 Orf1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the Ad-9 E4 Orf1. The immunogen is located within the last 50 amino acids of Adenovirus-9 E4 Orf1.

Isotype: IgG

Application Details

Application Notes: Ad-9 E4 Orf1 antibody can detect 10 ng Ad-9 E4 Orf1 peptide in ELISA at 1 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Adenovirus-9 E4 Orf1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Adenovirus-9 E4 Orf1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Adenovirus 9 E4 Orf1

Target: Adenovirus 9 E4 Orf1 (HAdV-9 E4-ORF1) (Human Adenovirus type 9 E4 Orf1 (HAdV-9 E4-ORF1))

Alternative Name: Adenovirus-9 E4 Orf1 (HAdV-9 E4-ORF1 Products)

Target Type: Viral Protein

Background: Adenovirus-9 E4 Orf1 Antibody: The many different serotypes of human adenoviruses (Ad) are divided into six subgroups, of which all Ad subgroup A and B and two subgroup D Ads can elicit tumors in infected rodents. Unlike the Ads from subgroup A and B, the ones from subgroup D, Ad9 and Ad10 elicit estrogen-dependent mammary tumors as opposed to undifferentiated sarcomas. In the case of Ad9, its tumorigenicity is dependent on the product of the open reading frame (ORF) 1 of the early region 4 (E4). The tumorigenic potential of Ad9 E4 Orf1 depends on a carboxyl-terminal PDZ domain-binding motif that mediates interactions with several different membrane-associated cellular proteins such as MUPP1, PATJ, MAGI-1, ZO-2 and Dlg1. It has been suggested that Ad9 E4 Orf1 may have evolved from an ancestral cellular dUTP pyrophosphatase.

Gene ID: 6386282

UniProt: P89079